Engineering a Better Way to Rebuild Bone Inside the Body

Traumatic bone injuries such as blast wounds are often so severe that the body can’t effectively repair the damage on its own. To aid the recovery, clinicians inject patients with proteins called growth factors. The treatment is costly, requiring large amounts of expensive growth factors. The growth factors also disperse, creating unwanted bone formation in the area around the injury.

Researchers Convert Discoveries in MSE to Real-World Applications

When scientists and engineers use the word materials, they mean any naturally occurring substance manipulated by humans to make things. Beginning with the first metals, discovered by trial and error thousands of years ago, the drive to develop materials that better serve human needs has played a central role in the rise of complex societies.

Modern researchers have moved past haphazard experimentation. Today they examine materials at every level – from the nanoscale to the visible and tangible macroscale – to understand why a material behaves as it does.

Mechanical Forces Affect T-Cell Recognition and Signaling

T-cells are the body’s sentinels, patrolling every corner of the body in search of foreign threats such as bacteria and viruses. Receptor molecules on the T-cells identify invaders by recognizing their specific antigens, helping the T-cells discriminate attackers from the body’s own cells. When they recognize a threat, the T-cells signal other parts of the immune system to confront the invader.